For a recent trip to Phoenix I thought the Arizona Biltmore would provide a pleasant place to stay, primarily for its good architecture and striking natural setting.
Although the hotel bears a strong resemblance to the works of Frank Lloyd Wright, it's not one of his buildings. The architect was Albert McArthur, who worked at one time as a draftsman for Wright.
The original portion of the hotel opened in 1929, with many consecutive additions over the years. I stayed in the newest addition, the Ocatilla building. There were a few kinks with the room, but overall the Biltmore served as a comfortable refuge for the few days I was in Phoenix.